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Module information

This is a largely practical module, which aims to develop experimental skills. A selection of practicals and follow-up sessions designed for students taking Pharmacology PHAR0004 provide reinforcement of the material in that module. This module is not capped.

On completion of the module students will be able to

• Conduct simple experiments on in vitro preparations and present their findings in a written account,
• Understand the use of animals in medical research from the standpoint of animal welfare and ethics.
• Set-up tissue preparations and use transducers and computers to measure tension or length changes in smooth muscle preparations.
• Understand the experimental conditions required to maintain tissues in vitro and of the requirements to achieve stimulation of nerves using pulse generators.
• Perform dilutions of stock drug solutions and calculate appropriate volumes to add to organ baths to achieve the desired final concentrations.
• Follow experimental protocols accurately to generate reproducible results
• Quantify results and present them clearly in graphical form.

There are no additional costs for this module – you will be provided with a lab coat and all the necessary laboratory equipment and consumables.

Indicative practical list:

Practical 1: Concentration-Response Curves Practical

Practical 2: Drug Antagonism Practical

Practical 3: Daphnia Practical

Practical 4: Tachykinin Practical

Practical 5: Cutaneous Blood Flow Practical

Practical 6: Stimulated Ileum Practical

Practical 7: Calcium Channel Blockers Practical

Follow-up tutorials will be held after each practical as well as on curve-fitting, report writing, literature searching and ethics.