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This module provides an introduction to essential concepts in systems physiology. You will learn about the importance of homeostasis; how cells communicate; ways of monitoring both the internal and the external environment; the resting membrane potential; initiation and propagation of action potential. These concepts will be applied to explain functioning of specific tissues. Two self-instructional practical sessions on Human Muscle and ECGs will allow you to research aspects of mammalian physiology you have encountered in lectures and reading.

By the end of the module you should be able to:

· Describe the normal functioning of the body from both lectures and reading.

· Understand some of the methods used to investigate physiological processes and the principles used to measure biological functions.

· Assess scientific evidence and analyse physiological data

Introductory Mammalian Physiology is compulsory for first year Human Scientists, Neuroscientists and Natural Scientists taking the Biomedical Sciences or Neuroscience and Psychology streams. Students on other degree programmes (including affiliate students) can take the module as an elective. This module is essential for students who wish to switch to a Physiology degree or take PHOL modules other than PHOL0005 in their second year.

Indicative lecture list (based on 2023/24 syllabus)

• Cellular physiology
• Skeletal muscle
• Cardiac and Smooth Muscle
• Physiology of the Blood
• Functional Layout of the Circulation
• Heart Electrical/ Contractile Properties
• Control of Cardiac Output
• Nerve Structure and Function
• Synaptic Transmission
• Introduction to the CNS and Reflexes
• Sensory and Motor Physiology
• Autonomic Nervous System
• The Respiratory System
• Gas Transport and Exchange
• Introduction to Endocrinology
• Introduction to Gut Physiology
• Gastrointestinal Secretions (2 lectures)
• Digestion and Absorption