ÐÂÏã¸ÛÁùºÏ²Ê¿ª½±½á¹û

Pharmacists are healthcare professionals who are experts in medicines, with a detailed understanding of the scientific basis of therapy. The MPharm programme integrates pharmaceutical science into the practice of clinical pharmacy, providing an education that equips graduates with the competencies and knowledge to provide safe and effective patient care. This module builds upon the fundamentals of pharmaceutical science and clinical pharmacy in Year 2 of the MPharm and runs in parallel with the Year 3 Clinical Therapeutics and the Scientific Basis of Practice C: Immunology, Inflammation and Infectious Diseases module. Together, they introduce students to the concept of clinical therapeutics and demonstrate how drug utilisation is firmly grounded in the pharmaceutical sciences. The Clinical Therapeutics and the Scientific Basis of Practice D: Cancer, Advanced Formulation and Therapeutics module is focused on the cell biology, pathophysiology, aetiology and epidemiology of cancer, alongside the pharmacology, medicinal chemistry and formulation of the drugs used to treat different cancers, within the context of the clinical and professional considerations involved in the pharmaceutical care of patients with cancer. The module will also focus on advanced and emerging pharmaceutical and therapeutic technologies more generally, including the role of the pharmacist in the application and oversight of these modalities. There is a strong emphasis on application and integration of knowledge and understanding, unconstrained by traditional subject boundaries, and the scientific rationale behind relevant therapeutic interventions. Throughout all aspects of the module, there is a strong focus on development of the diagnostic and clinical decision-making skills that are required to underpin safe and effective prescribing.

At the end of the module, students will have achieved the following learning outcomes and will be able to:

• Describe in detail cancer cell biology including cell cycle and the main biochemical and cell biological features that lead to malignant growth and haematological cancers
• Describe the aetiology, epidemiology and diagnosis of the most frequent cancersÌý
• Discuss the mechanisms of action, development, medicinal chemistry and formulation of drugs/drug classes used to prevent, diagnose, treat and manage common cancers, symptoms associated with the cancer; and the toxicities and side effects associated with cancer treatments
• Discuss the mechanisms of action, development and formulation of advanced therapeutic medicinal products, biologics, and the role of in the genomics in the prevention, treatment and management common cancers, symptoms associated with the cancer; and the toxicities and side effects associated with cancer treatments
• Demonstrate a critical awareness of the role of pharmacogenomics and personalised medicines and how they could and are influencing the diagnosis, prevention and treatment of conditions such as cancer, both now and in the future
• Describe the causes and clinical therapeutic management of common cancers, in light of specific patient factors and national guidelinesÌý
• Describe the more complex legal, ethical and professional aspects of pharmacy practice
• Demonstrate a critical awareness of public health issues, policies and interventions in the UK and worldwide and the role of pharmacy in health promotion and the prevention and management of disease
• Demonstrate a critical awareness of medicines safety issues and potential solutions to enhance safe medicines use
• Demonstrate appropriate professionalism and communication skills in a variety of simple and complex settings with patients, the public, health care professionals and the academic community
• Describe the current and future specialist areas of interest within pharmacy including current and future issues, and how such areas could or are influencing the practice of pharmacy now or in the future
• Demonstrate diagnostic and clinical decision-making skills, within the context of the module content and level of study, that are required to underpin safe and effective prescribing