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Description
All cell processes are regulated by signalling pathways. The correct regulation of cell processes is critical for the development and homeostasis of animals whereas dysregulation of these processes results in diseases as diverse as diabetes, schizophrenia and cancer. Taking advantage of the outstanding research environment at UCL, this course will consist of a series of lectures and associated journal clubs presented by research scientists of international renown. The lecturers will discuss the signalling pathways that regulate distinct cell processes such as such as proliferation, cell:cell communication, motility, differentiation, fertilisation and cell death. Each researcher will focus on their own research strengths to present an overview of the field, followed by a presentation of work from their own laboratory. The associated journal club will discuss a recent innovative piece of work related to the research area.
Indicative Lecture lists (based on 2023/24 syllabus)
- Introduction to Cell Signalling
- Ras Signalling
- Insulin/IGF-1 Signalling in Growth, Metabolism and Ageing
- Inositol Pyrophosphate Signalling
- New Concepts in G Protein-Coupled Receptor Signalling
- Protein Degradation
- Wnt Signalling
- Prostacyclin Signalling in Heart Disease
- Inflammation
- Dynamics of Cell Cycle Transitions
- Stromal Immunology
- Vascular Endothelial Growth Factor (VEGF) in the Nervous System
- TGF-beta Superfamily Signalling: Mechanism and Function
- Signalling in Neuronal Repair
- Mechanical and Physical Signalling
- Cell Polarity
Module deliveries for 2024/25 academic year
Last updated
This module description was last updated on 8th April 2024.
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